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SCFAs play a crucial role in gut health and have anti-inflammatory effects

One included study [27] suggested that L-C can significantly ameliorate total cholesterol, blood sugar, and cardiac function and improve clinical symptoms of patients for heart failure patients with diabetes mellitus

The other main roles of arhalofenate are to activate AMPK, inhibit NF-B and NLRP3 inflammasomes to promote the polarisation of anti-inflammatory macrophages, as well as significantly reduce UA-induced inflammation (Salminen et al., 2011

10.1590/s1677-5538.Ibju.2020.0358 38 GraefeE

5-aminolevulinic acid photodynamic therapy protects against UVB-induced skin photoaging: A DNA-repairing mechanism involving the BER signalling pathway